The Expanded Disability Status Scale (EDSS) and the Functional Systems Score (FSS) together describe severity of disability in patients with MS. With the help of the FSS, the examiner rates your disability on the EDSS scale. It ranges from 0 to 10, with half points for greater specificity. EDSS. • Expanded Disability Status Scale. – Devised by John Kurtzke in the s and modified A modification of the original Kurtzke scale.

Author: Met Braran
Country: Colombia
Language: English (Spanish)
Genre: Health and Food
Published (Last): 18 February 2006
Pages: 298
PDF File Size: 2.88 Mb
ePub File Size: 12.58 Mb
ISBN: 285-8-50801-948-4
Downloads: 98330
Price: Free* [*Free Regsitration Required]
Uploader: Arashijar

The lack of statistical difference between initial and final treatment score in edzs EDSS for some groups AVO, R44, COP and MITcould suggest disease stabilization or a reduction of disabilities, but these groups had less patients than the others with statistical significant data.

Every-other-day interferon beta-1b versus once-weekly interferon beta-1a for multiple sclerosis: Kurtzke authored over peer-reviewed articles and received multiple awards for MS research including the Charcot Award from the MS International Federation. sxore

Kurtzke’s publications, visit PubMed. In need of almost constant catheterization. Os casos foram submetidos a tipos diferentes de tratamentos: Axonal transec tion in the lesions of multiple sclerosis. Addition of selected points within body system. Rating neurologic impairment in multiple sclerosis: Significant disability but self-sufficient and up and about some 12 hours a dess.

The variation between the initial and final EDSS scores showed a reduction in 43 patients MRI as an outcome in multiple sclerosis clinical trials. Essentially restricted to wheelchair; though wheels self in standard wheelchair and transfers alone. Moderate nystagmus or other mild disability.

Moderate scoe in one Function System, or mild disability in three or four Function Systems. J Neurol Neurosurg Psychiatry ; STAT5 mediates antiapoptotic effects of methylprednisolone on oligodencrocytes. Significant disability but up and about much of the day, able to work a full day, may otherwise have some limitation of full activity or require minimal assistance.



Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis: Disease-modifying therapy in MS: Severe nystagmus, marked extraocular weakness, or moderate disability of other cranial nerves. Effects of oral glatiramer acetate on clinical and MRI monitored disease activity in patients with relapsinf multiple sclerosis: Calc Function Calcs that help predict probability of a disease Ecore.

Some of these patients received treatment with corticosteroids during their MS relapse and presented with a complete clinical remission or minimal scote neurological deficits. Please fill out required fields.

Paraplegia, hemiplegia, or marked sheet. Minimal Record of Disability for multiple sclerosis. The following exclusion criteria were implemented: The time spent exhibiting the first symptoms and seeking medical help was variable for these SYT patients, which was partially due to the fact that they did not have residual neurological deficits or additional relapses.

The difference from the initial and final EDSS score had statistical correlation with time of sheef progression in months for the whole group of treatment, as well as for the sub-groups AZA and BET Pearson’s correlation r test, Table 4 and Fig 5.

EDSS Calculator online (multiple sclerosis)

Requires two walking aids — pair of canes, crutches, etc — to walk about 20m without resting. Sgeet of glatiramer acetate Copaxone and interferon beta-1b Betaferon in multiple sclerosis patients: Multiple Sclerosis MS Symptoms: Moderate disability in one Function System and more than minimal disability in several others.


The median EDSS group was 2. However, MIT has been reserved for cases that do not respond to immunomodulator IMM drugs because of its toxicity 5,6. Generally has effective use of arms.

Able to walk without aid or rest for m. This study has some features that must be considered in the final conclusions, such as the asymmetry between certain groups with a greater number of patients.

Expanded Disability Status Scale (EDSS) | MS Unites – Multiple Sclerosis (MS) Information Portal

Interferon beta-1b is effective in relapsing-remitting multiple sclerosis: Mild or moderate paraparesis or hemiparesis; severe monoparesis. Cost-effectiveness of four immunomodulatory therapies for relapsing-remitting multiple sclerosis: The other authors declare that they have no conflicts of interest.

A double blind study on azathioprine efficacy in multiple sclerosis: Reichardt HM, Gold R. Moderate decrease in mentation. Essentially restricted to bed much of day. Can wheel self but can not carry on in standard wheelchair for a full day and may require a motorized wheelchair.

Expanded Disability Status Scale (EDSS)

Most of the studies used the EDSS as an index of disability to detect reduction, stabilization or progression.

The choose of medication changes from drug availability, introduction of new drugs scote the market, Government supplied or preference for one of the several physicians in charge of patients over the years. Copolymer 1 Multiple Sclerosis Study Group. More recently, a new score was developed based on the initial EDSS score and the time of disease progression for each patient.